現(xiàn)貨Moradec AH-102-AF說明書

Moradec的新型二級(jí)抗體藥物綴合物（2°ADC）是預(yù)篩選ADC候選抗體引線的研究工具。

αHFc CL MMAF

抗人IgG Fc MMAF抗體與可裂解連接子

目錄號(hào)：AH-102-AF

αHFc CL MMAF是一種抗人IgG Fc特異性抗體，與單甲基金黃色素F（MMAF）結(jié)合，具有可裂解接頭。抗體部分是對(duì)人IgG的Fc區(qū)特異的多克隆抗體。單甲基auristatin F（MMAF）是一種細(xì)胞毒性小分子，通過阻斷微管蛋白的聚合來抑制細(xì)胞分裂。連接MMAF和抗體的可裂解接頭在細(xì)胞外液中是穩(wěn)定的，但在進(jìn)入細(xì)胞時(shí)可被內(nèi)體組織蛋白酶裂解。

IgGs Anti-Human IgG (Fc Specific) ADCs

Product Name	Description	Catalog No	QTY	Price
αHFc-NC-MMAF	IgGs Anti-Human IgG Fc-MMAF Antibody with Non-Cleavable Linker	AH-101AF-50	50µg	$380
		AH-101AF-20	20µg	$190
αHFc-CL-MMAF	IgGs Anti-Human IgG Fc-MMAF Antibody with Cleavable Linker	AH-102AF-50	50µg	$380
		AH-102AF-20	20µg	$190
αHFc-CL-MMAE	IgGs Anti-Human IgG Fc-MMAE Antibody with Cleavable Linker	AH-102AE-50	50µg	$380
		AH-102AE-20	20µg	$190
αHFc-CL-DMDM	IgGs Anti-Human IgG Fc-Duocarmycin DM Antibody with Cleavable Linker	AH-102DD-50	50µg	$380
		AH-102DD-20	20µg	$190
αHFc-CL-PNU	IgGs Anti-Human IgG Fc-PNU159682 Antibody with Cleavable Linker	AH-102PN-50	50µg	$380
		AH-102PN-20	20µg	$190
αHFc-NC-DM1	IgGs Anti-Human IgG Fc-DM1 Antibody with Non-Cleavable Linker	AH-103D1-50	50µg	$380
		AH-103D1-20	20µg	$190
αHFc-CL-PBD	IgGs Anti-Human IgG Fc-PBD Antibody with Cleavable Linker	AH-106PB-50	50µg	$380
		AH-106PB-20	20µg	$190
αHFc-CL-DX8951	IgGs Anti-Human IgG Fc-DX8951 Antibody with Cleavable Linker	AH-107DX-50	50µg	$380